10 Top-Rated Hotels in Cape Girardeau, Missouri

July 13, 2022 Janette Largent

Discover the best hotels in Cape Girardeau, Missouri including Pear Tree Inn Cape Girardeau Near the Medical Center, Hampton Inn Cape Girardeau I-55 East, Drury Inn & Suites Cape Girardeau, Pear Tree Inn Cape Girardeau West, Auburn Place Hotel & Suites, Holiday Inn Express & Suites Cape Girardeau I-55, an IHG Hotel, Quality Inn, Candlewood Suites Cape Girardeau, an IHG Hotel, Town House Inn Cape Girardeau, Courtyard Cape Girardeau Downtown.
Things to do in Cape Girardeau

1. Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau, MO 63703-4960 1 (877) 378-2969
Excellent
48%
Good
29%
Satisfactory
16%
Poor
4%
Terrible
3%
Overall Ratings

4 based on 212 reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn by Drury provides an outstanding balance of quality, amenities and value. Guests can enjoy a free breakfast daily, free wireless Internet access in all rooms and throughout the hotel, free local calls and 60 minutes of free long distance calls. We look forward to having you as our guest!

So wonderful and helpful

Reviewed By maryhR3956OM

We were in a car accident. Totaled the car and we landed here, since one of us had to go to the hospital. The ladies there were a life saver....for us all. They helped us with everything. Was a clean, quiet stay and we could never Thank them enough! They were our own angels. Thanks!

2. Hampton Inn Cape Girardeau I-55 East

207 S Mount Auburn Rd, Cape Girardeau, MO 63703-4912 1 (855) 605-0317
Excellent
89%
Good
9%
Satisfactory
1%
Poor
0%
Terrible
0%
Overall Ratings

5 based on 484 reviews

Hampton Inn Cape Girardeau I-55 East

incredible service at our Cape Girardeau, MO hotel. From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street, our hotel complex includes various shopping and dining options. Walk to seven restaurants within the complex such as Cracker Barrel, Texas Roadhouse and Panera Bread. This beautiful new hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. If you're pressed for time, grab Hampton's On the Run™ Breakfast Bags, available Monday through Friday. Stay connected to the office with free WiFi in every room or work in the business center with two computer terminals and printing capabilities.

Great Experience on a Busy Weekend

Reviewed By Melissa R

We just checked out of the Hampton Inn this morning after a wonderful one night stay. We’re in town for a youth basketball tournament and this location was convenient for that. The hotel was clean and the staff were all incredibly friendly and accommodating, even on a busy weekend (hotel and surrounding area were full due to several sports tournaments as well as SEMO graduation). We’ll definitely be back!

3. Drury Inn & Suites Cape Girardeau

3303 Campster Dr, Cape Girardeau, MO 63701-8472 1 (866) 624-0725
Excellent
69%
Good
23%
Satisfactory
5%
Poor
2%
Terrible
0%
Overall Ratings

4.5 based on 268 reviews

Drury Inn & Suites Cape Girardeau

Travel Happy® with Drury Hotels. You have enough to worry about while you're traveling. Let us take a few things off your plate, so you can focus on the good stuff. Breakfast, Wi-Fi, dinnertime snacks, soft drinks, popcorn, business center, workout facilities and more - we've got you covered! A microwave and refrigerator can be found in all rooms. Drury Hotels is 100 percent family-owned and operated. At every one of our 150+ locations, you'll consistently experience rooms with crisp sheets, fine linens and cozy surroundings to ensure a good night's sleep.

Good stay!

Reviewed By Michael J

We rented a two room suite that was very comfortable. They have a breakfast in the morning and, bonus, a dinner in the evening! Great spot to stop on your travels and you have your meals covered! We stayed 2 times!

4. Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy, Cape Girardeau, MO 63701-8418 1 (866) 601-1065
Excellent
45%
Good
34%
Satisfactory
15%
Poor
4%
Terrible
2%
Overall Ratings

4 based on 262 reviews

Pear Tree Inn Cape Girardeau West

Pear Tree Inn by Drury provides an outstanding balance of quality, amenities and value. Guests can enjoy a free breakfast daily, free wireless Internet access in all rooms and throughout the hotel, free local calls and 60 minutes of free long distance calls. We look forward to having you as our guest!

GREAT staff, decent stay

Reviewed By SoCalV

Pros: Front desk staff very professional, courteous, and helpful Clean and comfortable beds Pet-friendly property Good breakfast offered Major downside: Thin walls; can hear hall traffic and guests in adjacent (side and above) rooms

5. Auburn Place Hotel & Suites

3265 William St, Cape Girardeau, MO 63703-4961
Excellent
63%
Good
21%
Satisfactory
8%
Poor
4%
Terrible
4%
Overall Ratings

4.5 based on 508 reviews

Auburn Place Hotel & Suites

Awesome place

Reviewed By Shyla4952

Very clean, comfortable room. The staff were very friendly and accommodating. The breakfast buffet was fabulous. I'd definitely recommend this place and would stay again if traveling here. I didn't use the pool or workout room but they looked great.

6. Holiday Inn Express & Suites Cape Girardeau I-55, an IHG Hotel

3253 William Street, Cape Girardeau, MO 63701
Excellent
71%
Good
23%
Satisfactory
3%
Poor
2%
Terrible
0%
Overall Ratings

4.5 based on 346 reviews

Holiday Inn Express & Suites Cape Girardeau I-55, an IHG Hotel

Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa.

Very good choice on a long trip!

Reviewed By maryrose1122

Convenient location. Clean. Nice linens. Refr, microwave, coffee maker. Good mattress, nice shower. Driving alone on a long trip and was able to rest! Felt safe in location. Easy check in and check out. I appreciate consistency within a brand.

7. Quality Inn

2011 N Kingshighway St I-55 exit #99, Cape Girardeau, MO 63701-2127
Excellent
11%
Good
24%
Satisfactory
28%
Poor
17%
Terrible
19%
Overall Ratings

3 based on 429 reviews

Quality Inn

Just one mile off of Interstate 55 Exit 99 toward Cape Girardeau. Convenient to Sports Plex, Southeast Hospital, Cape Splash and many other local attractions and restaurant choices.

Amazing Nights Sleep

Reviewed By Charlie1999xx

The best nights sleep we had so far on our road trip - such comfy beds, and despite being closed to a big road there was no noise. Clean room, and an average breakfast in the morning that you'd expect for a hotel of this price (only cooked items were sausage and egg). Would stay again if in the area.

8. Candlewood Suites Cape Girardeau, an IHG Hotel

485 S Mount Auburn Rd, Cape Girardeau, MO 63703-4926
Excellent
43%
Good
26%
Satisfactory
13%
Poor
10%
Terrible
9%
Overall Ratings

4 based on 136 reviews

Candlewood Suites Cape Girardeau, an IHG Hotel

Our beautiful Candlewood Suites hotel is located in historic Cape Girardeau in Southeastern Missouri. Cape Girardeau is bordered on the east by the mighty Mississippi River, 90 Minutes South of St. Louis. The only all-suite hotel in the area, the Candlewood Suites® Cape Girardeau hotel's spacious suites offer travelers room to work and a place to relax, as well as convenient access to the best attractions in Cape Girardeau, MO. The hotel's location is just off I-55, Exit 95, in Southeastern Missouri, convenient to the West Park business district, as well as St. Francis hospital and Southeast hospital. Business travelers appreciate such amenities as free high-speed, wireless Internet access and a 24-hour Business Center with printing capabilities. Our Extended Stay travelers love the Comforts of Home with our full kitchens in every Suite!The hotel's Cape Girardeau location is also exciting for leisure travelers. Nearby Southeast Missouri State University provides year-round opportunities for sporting events and cultural activities. Nature lovers enjoy the area's beautiful vistas and numerous parks, including the Trail of Tears State Park.

Comfortable, practical, not very fancy.

Reviewed By nataliektripexpert

I stayed at the Candlewood suites hotel for 4 days. There was a volleyball tournament and the whole team was able to have a room there. It was a nice hotel with a conference room and a small arcade. There was also a shop on the main floor. It was a clean hotel but outdated and a little bit worn down. There was a kitchenette that had a full size fridge with an ice maker, a coffee maker, a toaster, and a small stove. It also had dishes. Overall, a good hotel.

9. Town House Inn Cape Girardeau

505 North Kings Highway, Cape Girardeau, MO 63701-4333
Excellent
21%
Good
11%
Satisfactory
13%
Poor
13%
Terrible
43%
Overall Ratings

2.5 based on 47 reviews

Town House Inn Cape Girardeau

The Town House Inn Cape Girardeau is located just 2 miles away from the Southeast Missouri State University, show me center sports venue, Isle Casino and Downtown. Our Rooms feature Free Wi-Fi, HD satellite TV, Microwave, Fridge, and Coffeemakers. There is free parking available including truck parking and restaurants nearby.

Ghetto

Reviewed By davidcC1398XA

I needed a place to stay overnight that allowed pets. This came up from my search and I made a reservation. This was the nastiest place I have ever slept. The pictures speak for themselves but beyond the room there was a homeless guy sleeping behind the restaurant in the parking lot. I was worried about my vehicle parked right outside my room. I would have been better off pitching a tent somewhere.

10. Courtyard Cape Girardeau Downtown

400 Broadway St, Cape Girardeau, MO 63701-5622
Excellent
70%
Good
20%
Satisfactory
6%
Poor
0%
Terrible
4%
Overall Ratings

4.5 based on 50 reviews

Courtyard Cape Girardeau Downtown

Whether traveling for business or fun,Courtyard by Marriott® makes all of your travels successful by providing exactly what you need: spacious,thoughtful guest rooms;a hot breakfast offering and services that help you be more productive and comfortable.

Beautiful fun and convenient

Reviewed By DennisMissouri

We were at Cape Girardeau for State Cheer Competition. We stayed at this location and it was very convenient to multiple nice places to eat. It had a nice bar and coffee area. Loved the the room and the view was beautiful. Staff were very friendly. Would most definitely visit again

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